Яндекс Еда представили Ultima Guide, первый ресторанный гид, созданный с использованием высоких технологий. Нейросеть Яндекса проанализировала все заведения Москвы, Санкт-Петербурга и Сочи и представила топ-50 лучших ресторанов (в случае Сочи — топ-20).
Как происходило составление гида. Сначала нейросеть Яндекса, в которую загрузили информацию обо всех заведениях города, а также более чем 1600 подборок, составленных сотрудниками Яндекса, и публичных списков от популярных информационных ресурсов, оценила и систематизировала рестораны. Параллельно были проанализированы агрегированные данные о посещении ресторанов пользователями, которые предоставили доступ к такой информации.
Затем прошло голосование. Голосующих разделили на две группы: эксперты (шеф-повара, рестораторы и владельцы ресторанных групп, поставщики, гастрокритики и фуди), которые заполняли анкету на специальном сайте, и пользователи, которые прошли опрос в приложениях Яндекса.
Все данные собирались автоматизированно, чтобы исключить влияние человеческого фактора. Результаты посчитали с помощью специально разработанной аналитической модели Яндекса. В гид вошли 50 ресторанов (в случае Сочи — 20), получивших наиболее высокие оценки пользователей и экспертов.
Список ресторанов можно узнать здесь.
Источник: Яндекс

average cost of steroids
References:
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Lastly, as a result of the research was carried out completely online and solely students
with access to social media networks were included, generalizing the findings to
the entire pupil physique would be dangerous.
The market for efficiency enhancing drugs is
now huge and continuously growing. In reality, the phenomenon of doping not affects only
professional athletes, but additionally topics training sports activities activities at the novice
degree (Reardon and Creado, 2014). Given the escalating development of AAS utilization, significantly amongst non-bodybuilding people, it
is imperative that GPs can accurately establish and subsequently contextualise abnormal blood check ends in these sufferers.
This will forestall inappropriate referrals to secondary care and probably save unwarranted investigations
for the patient. For acute kidney injury (AKI) stage 1, a evaluate change in creatinine
must be advised.
There have been no variations between the two groups with respect to age, peak, systolic blood stress, or training hours per week.
AAS users exhibited significantly elevated maximal energy levels in each bench press and ground raise when compared to WLC.
These findings suggest a somewhat high proportion of former AAS abusers exhibit testosterone ranges in the low space of the normal vary years after AAS cessation, whereas solely a small proportion of former AAS abusers exhibit persistently marked low
testosterone ranges. These results point out that a substantial proportion of former AAS abusers exhibited persistent ASIH
options, similar to biochemical and useful hypogonadism, years after AAS
cessation.
Due To This Fact, individual attempts to discover a ‘less dangerous dose’ are tailored by way of trial-and-error [11, 70].
We aimed to recruit a sample with a variety of demographic traits and experiences with the use of anabolic steroids.
This theoretical sample [25] would ideally illustrate
a spread of risk-management strategies adopted by different users [26].
The inclusion standards were being at least sixteen years old, residing
in the UK on the time of the study, and having used anabolic steroids without a medical
prescription throughout the past 12 months. Based on the cohort of similar studies [27,28,29,30,31], we estimated that
a minimal of 20 participants can be required to attain theoretical saturation, i.e.,
when further data collection wouldn’t provide further theoretical perception to the evaluation [32].
We suggest that AAS induces this neurobehavioral state, which can be defined as
emboldenment. For instance, AAS-treated males show elevated sexual motivation in a associate choice take a look at, continue copulatory attempts with sexually receptive females
having vaginal occlusion, and copulate with sexually receptive females
in a high risk check. Specifically, pubertal AAS abuse might contribute to abnormal brain improvement, or no much less than alter the
normal trajectory of brain development, leading to
increased vulnerability for psychopathological and issues and maladaptive behaviors.
At the light of this revision work, a pivot position might be performed by miRNAs
that seems dysregulated in the cardiovascular or liver illnesses,
as a outcome of these organs are inquisitive about adverse effects
after AASs use/abuse. For example, it could be very important
carried out experimental work dosing MyomiRNAs which would possibly be a subset of
muscle-specific miRNAs. This group includes a discrete number of
molecules (miRNA 1, miRNA 29-b, miRNA 133, miRNA 181-a,
miRNA 206, miRNA 208 and miRNA 451). Among these, miRNA 133-a and
miRNA 206 have been found to be probably the most promising for understanding the biological response to physical exercise and
for the potential use for diagnosing muscle damage and in anti-doping
testing (Danese et al., 2017).
The finest treatment for low testosterone levels is to stay energetic, raise weights,
eat nutritious food, take a testosterone booster complement and reduce unnecessary stress (late nights, fear etc.).
Once LH gets to your gonads, it tells them to dump
extra T into the bloodstream as ranges are getting low.
And then to cease concentrations getting too high (remember, the
traditional higher restrict is 1,000 ng.dL), the hypothalamus slows down the discharge of GnRH and therefore the gonads cease
making as a lot. As understanding precisely how and where this powerful hormone is produced helps to differentiate it
from synthetic steroids. You find that your health and energy is non-existent and you’re
at a significantly greater threat of being overweight, low on energy
and a shadow of your former self.
A 24 year old physique builder developed pruritus and jaundice having taken numerous anabolic steroids for one and a half years.
He was also taking a number of herbal merchandise
and dietary dietary supplements together with Ma Huang (6%
ephedrine), carnitine and chromium. He additionally drank alcohol,
estimating his common intake as one case of beer per day for
the final yr.
A referral to a sexologist is suggested for these
in whom a psychogenic trigger is in all probability
going – which is widespread in our expertise.
A few stories within the literature have linked
AAS use to focal segmental glomerulosclerosis
(FSGS) (169–171). FSGS is a histopathological finding marked by glomerular lesions, mediated by numerous insults
directed to, or inherent within, the podocytes (172).
Testosterone is irreversibly converted by the enzyme 5α-reductase to 5α-dihydrotestosterone (DHT), which binds with higher affinity to the androgen receptor (AR), or by aromatase to oestradiol, which binds
to the oestrogen receptor (ER). Testosterone and DHT could
be also transformed to weaker androgens (not displayed),
once more being depending on whether the goal tissue has
the mandatory enzyme exercise, e.g., 3α-hydroxysteroid dehydrogenase,
17β-hydroxysteroid dehydrogenase. As long as anabolic steroid misuse
is popular amongst younger athletes, data campaigns concerning AASs and different
doping brokers ought to be inspired in high schools.
In this regard, to forestall the utilization of AASs public well
being measures in all settings are essential.
Physicians caring for each adults and adolescents ought to be alert to
the indicators of AAS abuse and train patients about its dangers.
Education about AASs should start by the start of center
faculty, using applications that train various, healthy ways to extend muscle dimension and improve performance through good
vitamin and weight training strategies. Presenting both dangers and
benefits of AAS use appears to be a more effective approach to educate adolescents about the adverse results of illicit steroid use.
A well-known complication of AAS use is infertility, due to the suppression of the hypothalamic-pituitary-gonadal (HPG) axis and subsequent suppression of spermatogenesis in the testes.
Cessation of AAS use can restore spermatogenesis,
however restoration can take several months to years (1).
Many of these sufferers are of their prime reproductive years,
and depending on elements such because the age of the feminine partner and variety of youngsters
desired, there may be a strong need to revive fertility as quickly as attainable.
Current and former use have been taken into consideration in additional analyses, as some participants may be categorized as «dependent»
whereas not presently utilizing, and vice versa, which can have
an impact on the findings. In addition, the AAS using group includes women with a variety of years
of cumulative use (1–26 years). The study also depends on self-report
measures, including the ASEBA and BPAQ, with some scales of the ASEBA having lower than acceptable reliability as indicated
by Cronbach’s alpha. The categorization of the ASEBA scalers
indicate normal/borderline/clinical ranges, however the ladies on this research were not formally evaluated or diagnosed
with ADHD or other disorders.
References:
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